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FDA Grants Approval to Innovent Biologics' IBI363 for Global Phase III NSCLC Clinical Trial

The advancement of novel immune therapies underscores intensifying competition in the oncology...
Key Metrics

12.62

Heat Index
  • Impact Level
    Medium
  • Scope Level
    Global
  • Last Update
    2025-08-25
Key Impacts
Positive Impacts (3)
Innovent Biologics
PD-1/PD-L1 Immuno-oncology Drug Market
Contract Research & Manufacturing Organizations (CRO/CDMO sector)
Negative Impacts (1)
Merck & Co. (Keytruda)
Total impacts: 4 | Positive: 3 | Negative: 1
Event Overview

The advancement of novel immune therapies underscores intensifying competition in the oncology sector, with regulatory clearance marking a critical milestone for late-stage clinical development. This event highlights the significance of global collaboration in clinical research, heightened industry focus on immune-resistant cancer types, and the importance of head-to-head studies with established treatments for regulatory and market positioning in the pharmaceutical field.

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Innovent Biologics' IBI363 Receives FDA Approval for Phase III NSCLC Trial
2025-08-25 08:30

On August 25, Innovent Biologics announced that its independently developed PD-1/IL-2α-bias bispecific antibody fusion protein, IBI363, received approval from the United States Food and Drug Administration (FDA) to initiate its first global Phase III clinical trial (MarsLight-11) for the treatment of immune-resistant squamous non-small cell lung cancer (NSCLC) patients. Additionally, IBI363 is being compared head-to-head with pembrolizumab (Keytruda) in an ongoing pivotal registration study for the treatment of melanoma in China.

Total records: 1
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