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RemeGen's Telitacicept Achieves Positive Phase III Results for IgA Nephropathy in China

Innovative drug development and clinical validation processes highlight advances in biopharmaceutica...
Key Metrics

10.32

Heat Index
  • Impact Level
    Medium
  • Scope Level
    National
  • Last Update
    2025-08-27
Key Impacts
Positive Impacts (3)
RemeGen Co. Ltd. (9995.HK)
China Domestic Biotech / Innovative Pharma Indexes (e.g., Hang Seng Mainland Healthcare Index)
WuXi Biologics and other China-based CDMOs
Negative Impacts (4)
Calliditas Therapeutics AB
Travere Therapeutics Inc.
Generic Corticosteroid Producers in China
Chinese Health-Insurance Providers
Total impacts: 7 | Positive: 3 | Negative: 4
Event Overview

Innovative drug development and clinical validation processes highlight advances in biopharmaceutical research targeting autoimmune-related kidney diseases. Competitive progress in the pharmaceutical landscape is illustrated by milestone achievements in trials designed to address unmet medical needs. Regulatory and market implications arise as first-in-class biologics demonstrate significant efficacy, paving the way for potential new therapies and intensifying commercialization and patient access considerations.

Collect Records
RemeGen's Telitacicept Reaches Primary Endpoint in Phase III IgA Nephropathy Trial in China
2025-08-27 18:32

RemeGen announced that its independently developed, first-in-class BLyS/APRIL dual-target fusion protein drug Telitacicept (brand name: Tai'ai) met the primary endpoint in the A stage of a Phase III clinical trial for the treatment of IgA nephropathy (IgAN) in China. Telitacicept was administered at a dose of 240 mg by subcutaneous injection once per week. Analysis of the A stage showed that, compared to the control group, patients in the Telitacicept group had a 55% reduction in 24-hour urine protein-to-creatinine ratio (UPCR) at week 39 of treatment (P<0.0001), and demonstrated good tolerability and safety.

Total records: 1
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